View Our Website View All Jobs

Director, Cell Manufacturing Science & Technology

Director, Cell MS&T



Key leadership role responsible for optimizing T-cell manufacturing for new patient therapies, enabling a deep understanding of T-cell processes and products, and driving implementation of cutting-edge technologies. 



  • Manage & lead a team of 10-15 people responsible for ensuring successful manufacturing of new cell products and existing product lines. 
  • Lead cross-functional teams to deliver optimized processes to global T-cell manufacturing venues.  
  • Develop an efficient manufacturing deviation root cause investigation and reporting system and establish effective corrective and preventive actions. 
  • Liaison with Manufacturing, Process Development, Quality Assurance, Quality Control, Regulatory, Clinical and various project stakeholders to promote Product Development aims
  • Manage process and product analytic strategy.  Oversee process analytics and data management for development, regulatory and clinical objectives. 
  • Drive innovation. Develop and implement tools, systems, and processes to identify and implement innovative cell manufacturing processes. 
  • Manage internal and external collaborations to attract key technologies.  Educate and train Adaptimmune team members and stakeholders on new technologies. 
  • Establish and lead teams to source, vet, qualify, and implement cell manufacturing equipment, supplies, reagents, infrastructure, and IT.
  • Effectively & efficiently communicate results internally and externally.  Prepare data reports for internal use, regulatory filings, investor publications, and scientific conferences.   
  • Participate in CMC leadership team to set annual objectives, manage global supply chain, optimize and improve manufacturing processes, and maintain state-of-the-art quality management systems



  • BS in Pharmaceutical Sciences, Physical Sciences or related Life Sciences, advanced degree desired
  • Minimum of 10 years of experience in biotech or pharmaceutical industry, preferably in MS&T with emphasis on immunological systems, cell therapy, gene therapy, and individualized patient therapies
  • Hands on experience with Drug Product manufacturing scale up, technology transfer, product process optimization & experience with RCAs and CAPAs
  • Thorough understanding of drug development and commercialization process including strong knowledge of cGMP regulations and/or clean room experience
  • Experience in authoring and reviewing documents for regulatory (FDA, EMA) review including IND, CTA, BLA and other regulatory filings
  • Experience bringing new products through development to commercialization
  • Experience working with human T-cells, primary human cells, immunological systems or similar biological systems
  • Must have excellent interpersonal & communication skills; strong customer focus required given the need to provide strategic insight to the CMC Leadership Team and integrate activities with CMOs, cross-functional partners and collaborative partners
  • Demonstrated leadership and teamwork skills
  • Experience with managing direct reports and leading teams of 5-15 people and/or leading project teams in a highly matrixed environment
Read More

Apply for this position

Apply with
Attach resume as .pdf, .doc, .docx, .odt, .txt, or .rtf (limit 5MB) or Paste resume

Paste your resume here or Attach resume file