Adaptimmune

Senior Engineer-Equipment and Utilities

Facilities - Philadelphia, PA - Full Time

Adaptimmune is a fully integrated commercial-stage cell therapy company, designed and built from the ground up with UK- and U.S.-based biotechnology hub locations. Our comprehensive capabilities and teams include preclinical research, clinical development, translational sciences, autologous and allogeneic manufacturing, and in-house commercial and corporate operations.

Our company culture is rooted in trust, inclusion, our capacity to collaborate, and our commitment to being honest and brave in our desire to successfully transform the lives of people with cancer.

THIS IS AN ON-SITE ROLE BASED OUT OF OUR PHILADELPHIA, PA LOCATION.

The Senior Engineer is responsible for supporting operations by ensuring that the building, utilities and manufacturing equipment are properly maintained to support GMP manufacturing and general facility operations. This support includes performing building, utility and manufacturing equipment inspections, diagnosing problems, scheduling, coordinating and overseeing third party maintenance activities, performing hands-on maintenance, , and completing and reviewing GMP and non-GMP documents relating to change controls.  Working closely with CMC personnel to ensure the facility and equipment is kept in an inspection ready condition. 

Scope includes and not limited to:

  • Understand core CMC goals and operations to ensure maintenance strategies mesh with stakeholder requirements and business needs.
  • Oversee the building and utility maintenance program in accordance with GMP and GDP requirements to achieve a high level of equipment reliability and inspection readiness.  Assess repair effectiveness against preventive maintenance strategies, and develop and/or enhance PMs accordingly.
  • Investigate equipment and utility deficiencies using root cause analysis, creative problem-solving techniques, and technical expertise to identify and resolve causal factors.
  • Schedule, oversee and verify 3rd party manufacturing equipment / utility (mechanical, HVAC, electrical, gases) / building maintenance activities. Obtain and process vendor quotes for repairs and services.
  • Lead or assist with building/utility-related projects. 
  • Participate in the budget process by tracking expenses and forecasting annual maintenance costs.
  • Respond to after-hours building and utility alarms on a rotational basis. 
  •  Perform daily inspection of buildings and utility equipment to proactively identify and document areas of concern.
  • Own and manage the compressed gas program
  • Initiate and participate in GMP investigations, deviations, CAPAs and change controls related to building, utility and equipment repairs.  Develop and modify SOPs related to equipment maintenance
  • Assist with building support services
  • Occasionally perform building and utility maintenance, such as patching / painting, filter replacement, etc.  Some work may be required in a GMP clean room (gowning required).

This role requires creative and collaborative interfacing with CMC stakeholders, facility operations and facility engineering teams.  Scope of work includes championing effective equipment / utility maintenance practices and strict adherence to GMP requirements.

Key Responsibilities

  • Oversee the utility and building maintenance program, including preventive and corrective maintenance programs. Some maintenance activities will be performed in a clean room.
  • Lead or assist with Facilities and Engineering projects, including equipment installations and HVAC upgrades. 
  • Perform building and manufacturing equipment inspections to proactively identify maintenance and calibration needs. 
  • Perform or oversee maintenance (or repairs) on facility utility systems and manufacturing / laboratory equipment.  Some maintenance activities will be performed in a clean room.
  • Perform all activities in compliance with applicable cGMP regulations, FDA, USP and ISPE guidelines
  • Oversee and change out compressed gases on process equipment.
  • Assist building support services in setting up conference rooms, meetings, events, hanging white boards, kitchen and office inventory, etc.
  • Other duties as assigned by management in support of rapidly growing company.

Qualifications & Experience

  • Requires 5 years of relevant facility, utility and equipment maintenance experience within a GMP manufacturing environment.   
  • Demonstrated oversight, knowledge and expertise with overseeing HVAC maintenance programs
  • A work-ethic focused on precision and accuracy.
  • Excellent communication skills with a proven track record of working in a collaborative and team environment.
  • Solid analytical and critical thinking skills with experience in effective troubleshooting of equipment and utility deficiencies
  • Excellent partnering skills – able to collaborate with technical and non-technical staff across the organization.
  • Expert in GMP requirements on facility, utility (mechanical, HVAC, electrical, gases) and/or manufacturing equipment
  • Must be available to respond to after-hours equipment emergencies on a scheduled rotational basis
  • Experience with computerized maintenance management system (Blue Mountain or equivalent)
  • Must be able to lift 30 pounds
  • 5 days a week in office situation (not a work from home role)

At Adaptimmune we embrace diversity and equality of opportunity. We believe that the more inclusive we are, the better our work will be. We welcome applications to join our team from all qualified candidates, regardless of age, colour, disability, marital status, national origin, race, religion, gender, sexual orientation, gender identity, veteran status or other legally protected category. It is our intent that all qualified applicants will receive equal consideration for employment.

Apply: Senior Engineer-Equipment and Utilities
* Required fields
First name*
Last name*
Email address*
Location *
Phone number*
Resume*

Attach resume or Paste resume

Attach resume as .pdf, .doc, .docx, .odt, .txt, or .rtf (limit 5MB) or paste resume

Paste your resume here or attach resume file

By continuing with and submitting your application, you are agreeing to the following:

1. You have read and understood the statements made in the consent form and the ways in which your personal data will be stored and processed.
2. To the storing and processing of your personal information by Adaptimmune, members of the Adaptimmune group of companies and third parties working on behalf of Adaptimmune as set out in the consent form.
3. To the storing and processing of your personal information outside of the European Union and to the transfer of personal information between the EU and the United States.
4. To the storing of personal information for the periods set out in the Privacy Notice.
5. You understand that you can withdraw your consent at any time.*
Do you have the independent right to live and work in this country without the need for Visa sponsorship?*
The following questions are entirely optional.
To comply with government Equal Employment Opportunity and/or Affirmative Action reporting regulations, we are requesting (but NOT requiring) that you enter this personal data. This information will not be used in connection with any employment decisions, and will be used solely as permitted by state and federal law. Your voluntary cooperation would be appreciated. Learn more.
Gender
Race/Ethnicity
Invitation for Job Applicants to Self-Identify as a U.S. Veteran
  • A “disabled veteran” is one of the following:
    • a veteran of the U.S. military, ground, naval or air service who is entitled to compensation (or who but for the receipt of military retired pay would be entitled to compensation) under laws administered by the Secretary of Veterans Affairs; or
    • a person who was discharged or released from active duty because of a service-connected disability.
  • A “recently separated veteran” means any veteran during the three-year period beginning on the date of such veteran's discharge or release from active duty in the U.S. military, ground, naval, or air service.
  • An “active duty wartime or campaign badge veteran” means a veteran who served on active duty in the U.S. military, ground, naval or air service during a war, or in a campaign or expedition for which a campaign badge has been authorized under the laws administered by the Department of Defense.
  • An “Armed forces service medal veteran” means a veteran who, while serving on active duty in the U.S. military, ground, naval or air service, participated in a United States military operation for which an Armed Forces service medal was awarded pursuant to Executive Order 12985.
Veteran status
I IDENTIFY AS ONE OR MORE OF THE CLASSIFICATIONS OF PROTECTED VETERAN LISTED ABOVE
I AM NOT A PROTECTED VETERAN
I DON’T WISH TO ANSWER
Voluntary Self-Identification of Disability
Voluntary Self-Identification of Disability Form CC-305
OMB Control Number 1250-0005
Expires 04/30/2026
Why are you being asked to complete this form?

We are a federal contractor or subcontractor. The law requires us to provide equal employment opportunity to qualified people with disabilities. We have a goal of having at least 7% of our workers as people with disabilities. The law says we must measure our progress towards this goal. To do this, we must ask applicants and employees if they have a disability or have ever had one. People can become disabled, so we need to ask this question at least every five years.

Completing this form is voluntary, and we hope that you will choose to do so. Your answer is confidential. No one who makes hiring decisions will see it. Your decision to complete the form and your answer will not harm you in any way. If you want to learn more about the law or this form, visit the U.S. Department of Labor’s Office of Federal Contract Compliance Programs (OFCCP) website at www.dol.gov/ofccp.

How do you know if you have a disability?

A disability is a condition that substantially limits one or more of your “major life activities.” If you have or have ever had such a condition, you are a person with a disability. Disabilities include, but are not limited to:

  • Alcohol or other substance use disorder (not currently using drugs illegally)
  • Autoimmune disorder, for example, lupus, fibromyalgia, rheumatoid arthritis, HIV/AIDS
  • Blind or low vision
  • Cancer (past or present)
  • Cardiovascular or heart disease
  • Celiac disease
  • Cerebral palsy
  • Deaf or serious difficulty hearing
  • Diabetes
  • Disfigurement, for example, disfigurement caused by burns, wounds, accidents, or congenital disorders
  • Epilepsy or other seizure disorder
  • Gastrointestinal disorders, for example, Crohn's Disease, irritable bowel syndrome
  • Intellectual or developmental disability
  • Mental health conditions, for example, depression, bipolar disorder, anxiety disorder, schizophrenia, PTSD
  • Missing limbs or partially missing limbs
  • Mobility impairment, benefiting from the use of a wheelchair, scooter, walker, leg brace(s) and/or other supports
  • Nervous system condition, for example, migraine headaches, Parkinson’s disease, multiple sclerosis (MS)
  • Neurodivergence, for example, attention-deficit/hyperactivity disorder (ADHD), autism spectrum disorder, dyslexia, dyspraxia, other learning disabilities
  • Partial or complete paralysis (any cause)
  • Pulmonary or respiratory conditions, for example, tuberculosis, asthma, emphysema
  • Short stature (dwarfism)
  • Traumatic brain injury
Please check one of the boxes below:
YES, I HAVE A DISABILITY, OR HAVE HAD ONE IN THE PAST
NO, I DO NOT HAVE A DISABILITY AND HAVE NOT HAD ONE IN THE PAST
I DO NOT WANT TO ANSWER

PUBLIC BURDEN STATEMENT: According to the Paperwork Reduction Act of 1995 no persons are required to respond to a collection of information unless such collection displays a valid OMB control number. This survey should take about 5 minutes to complete.

Name Date
Human Check*